Life-style Modulation and Healthy Long-life

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About the congress

Aging is one of the main health-related challenges in the world.The healthcare costs in many countries are very high because of the increased number ofunhealthy populations and the consequent increase of severe age-related disabilities. This is achallenging problem for society, especially for the cost of the health-care system and the difficulty insocial engagement.

The gerontologists distinguish two ways to become old: without success (unsuccessful aging,UA) and with success (successful aging, SA).UA is manifested by people that develop one or moreage-related diseases and frailty. Regarding SA, the World Health Organization defines it as «theprocess of developing and maintaining the functional ability, which enables well-being in older age».The best model of SA is represented by centenarians that are a very selected and rare group ofpeople. They live 100 years or more in relatively good health status, escaping fatal or stronglyinvalidating diseases lifelong. Thus, they are a concrete example of resilience.

Thus, the goal for the next future should be how to achieve the so-called “health-span”(healthy life-span) more than the treatment of age-related disease to prevent the collapse of the health systemand the unsustainability of the society. It is well noted that some aspects of life-style like nutrition,physical and psychosocial activities can modulate the aging rate and can improve the lifespan, asdemonstrated by a huge amount of scientific evidence.

In order to find possible solutions, it is necessary to identify the best life-style(s) to reach andmaintain a healthy long-life by possible strategies for improving daily habits. This point will bediscussed during this congress, hosting international researchers

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  • Location Sala delle Capriate, Palermo
  • Date 05 October 2023
  • Speakers 12 Experts
  • Seats 60 Seats


  • Scientific Committee
  • Anna Aiello
  • Giulia Accardi
  • Calogero Caruso
  • Francisco Javier Ferrandez Pastor
  • Giuseppina Candore
  • Maria Loreto Macià Soler
  • Organising Committee
  • Edoardo Ricci
  • Vito Parrinello
  • Francisco Miguel Escandell Rico
  • Manuel Platero Horcajadas
  • Dario Saguto

Congress Schedule

Consult the list of conferences, speakers and their timetable.

8:15 AM Arrival
9:00 AM Welcome
9:30 AM Workshop

Antonia Trichopoulou MD, PhD, Member of the Academy of Athens, Professor Emeritus of the University of Athens, School of Medicine. Her scientific work focuses on public health and nutritional epidemiology, emphasizing health effects of the Mediterranean diet and traditional foods. Named in Thomson Reuters 2014 “World's Most influential Scientific Minds” List and awarded as a Highly Cited Researcher by Clarivate Analytics in 2018 and 2021, she is decorated with the Golden Cross of Honour for work in preventative medicine and nutrition by the President of the Greek Republic.

Mediterranean Diet, Longevity and Sustainable Food Culture

Antonia Trichopoulou1, M.D.

1 Professor Emeritus of the University of Athens, School of Medicine.

Recently it is advocated that healthy eating is a suitable approach for Sustainable diets and several efforts try to integrate food and nutrition into healthcare for prevention, management, treatment of diet related disease and longevity. 
Thus, Public Health strategy often focuses on improving energy balance and dietary changes towards predominantly plant-based diets, which are in line with evidence that healthy eating is a suitable approach for sustainable diets. 
The last decade Mediterranean diet has evolved from a healthy dietary pattern to a sustainable dietary pattern, with low environmental impacts in which nutrition, food, cultures, people, environment, and sustainability all interact with each other, promoting longevity. 
10:00 PM Workshop

Danay Saavedra, MD, MS, PhD: Medical Doctor, Superior Institute of Medical Sciences of Havana (2002). Visiting physician in Haiti (2004-2005). Master degree in Infectious Diseases, Superior Institute of Medical Sciences of Havana (2010). Immunology Specialist, Superior Institute of Medical Sciences of Havana. Senior researcher and specialist of Department of Clinical Immunology at the Center of Molecular Immunology since 2014 mainly dedicated to the study of immunology of ageing, human immunosenescence and the evaluation of immune response in patients diagnosed with lung cancer treated with immunotherapies. Scientific stay at Lausanne Branch/Ludwig Cancer Research (2017). Senior Faculty of the “Universidad de Ciencias Médicas de la Habana”. Have published more than 30 papers and participated in more than 30 National and International Congress as speaker.

Immunosenescence and inflammatory markers in Cuban centenarians: implications for survival

Saavedra, D.1

1 Center of Molecular Immunology, Havana, Cuba

Introduction: Centenarians are considered a model of successful aging. Cuba exhibits one of the oldest populations in Latin America with more than two thousand centenarians. This study aimed to evaluate the immune phenotype of forty-three Cuban centenarians. Additionally, to associate the immune phenotype and serum inflammatory markers with survival after 25 months. Results: The seroprevalence against cytomegalovirus was 100%. Concerning proinflammatory markers, the majority of them had very low cytokine levels and serum C-reactive protein around the normal limit. We found the predominance of memory subsets over naïve compartments in CD4+ and CD8+ T cells. Terminally differentiated CD8+CD28- T cells were higher in frail centenarians than in pre-frail, while CD8+CD57+ and CD8+EMRA T cells were higher in moderately and severely dependent individuals than in independent subjects. Severely dependent centenarians had a lower CD4+/CD8+ ratio. Thirty-eight centenarians received follow-up phone calls. Fourteen of them (36.8%) were alive at the moment of the follow-up communication (median:19.3 months (95% Confidence Interval 14.1-24.4 months). Absolute CD4+ T cell count was lower in the group of non-survivors, while the frequency of terminally differentiated T cells was higher. Using multivariate Cox regression, we found that higher frequencies of CD4+CD45RA+CD28-, CD8+CD28- T cells, and unswitched memory B cells were associated with higher mortality risk. Interestingly, no differences were found concerning serum levels of IL-6, TNF-α, and C-reactive protein, between survivors and non-survivors, and no associations were found between those serum inflammatory markers and survival. Conclusion: This study describes for the first time the predominance of memory subsets over naive compartments in CD4+ and CD8+ T cells, as well as its relation to frailty and/or dependency in a group of Cuban centenarians. Besides, higher proportions of terminally differentiated T cells were associated with higher mortality. However, no association was found among inflammatory serum markers and survival beyond 100 years of age. Further studies are needed to continue understanding the relationship between terminally differentiated lymphocytes and inflammaging in the context of extreme longevity in Cuba. 
10:20 AM Workshop

Calogero Caruso, formerly Full Professor of General Pathology, is Professor Emeritus at the University of Palermo, Italy. He graduated from the School of Medicine, University of Palermo, in 1971 (magna cum laude). He was founder and editor-in-chief of the journal Immunity & Ageing (2004-2018), and has authored 401 publications (15,478 citations), mostly on ageing, age-related diseases and longevity, indexed on Scopus (H index of 63). He has recently edited the book “Centenarians. An example of positive biology.” for Springer Nature and, with Prof. G. Candore, the book “Human Aging. From Cellular Mechanisms to Therapeutic Strategies.” for Academic Press”.
Presenting author details
Full name: Calogero Caruso
Contact number: +393297506840
Twitter account:@CalogeroCaruso9

The Sicilian Centenarians

Calogero Caruso1

1Laboratory of Immunopathology and Immunosenescence, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Italy

The study of centenarians is important for shedding light on the molecular mechanisms behind ageing to promote well-being and to possibly predict and/or avoid the development of age-related diseases. Herein, we will summarize the results of our studies performed in a sample of Sicilians, including centenarians as well as semi- and super-centenarians. In the last few years, we explored several phenotypic aspects of aging and longevity revealing age and gender-related variations in various biomarkers, emphasizing the importance of considering gender differences in ageing and longevity research. Interestingly, some parameters showed similarities between young adults and centenarians rather than between nonagenarians and centenarians, suggesting a possible slowdown or reversal of systemic deterioration as a marker of extreme longevity. Understanding the biological mechanisms of longevity in centenarians can offer valuable insights into slowing down the aging process, benefiting individuals prone to disease and disability. These findings have significant implications for translational medicine in an aging population.
10:40 AM Workshop

Full professor in Clinical Biochemistry and Molecular Clinical Biology
The main areas of interest of Prof. Carru concerns the set-up of new analytical procedures by HPLC and Capillary Electrophoresis for the biomarkers analysis as a support of the human health epidemiological studies (factors involved in cardiovascular diseases, acute and chronic disease, and human tumours). In particular, leading his group to study Genomics, Proteomics and Metabolomics biomarkers in the vascular and cardiovascular diseases, inflammation and oxidative stress in several diseases (CK, COPD, IPF, CAD), in the age related diseases and in in the human aging (AKeA - The Sardinia centenarians Study). Recent area of interest regards the study of Antioxidant and pro-oxidant food effect on the "cell signalling" as a radical oxygen species mediated, Blood cell count-derived as a inflammation biomarkers assessment in several pathologies, and, recently, study of the association between blood biomarkers and severity degree of the COVID-19 disease.

Teaching staff with a fixed-term contract in Clinical Biochemistry and Molecular Clinical Biology
Dr. Donatella Coradduzza, holds a degree in Chemistry and Pharmaceutical Technology. At the time is Researcher and Laboratory Chemistry as aggregate professor at Universita degli Studi di Sassari, formerly Secondary School Chemistry Lecturer. She has participated and coordinated several Erasmus KA1 projects at Pellegrini Institute in Sassari.She collaborates with Aispo for international cooperation projects for the development of the college of healt of Duhok University in Iraqi Kurdistan. He is first author and co-author of publications in scientific field - with National Research Council [CNR], kings college , Institute of Biophysics, 2nd Faculty of Medicine, Charles University, V Uvalu 84, 150 06 Prague 5, Czech Republic, University of Campania "L. Vanvitelli", Naples, Department of Twin Research and Genetic Epidemiology, King's College London, London, and others. PhD and specialized at Universidad Camillo Josè Cela of Madrid in Curso de apititude pedagogica. Various experiences in pharmaceutical companies such as Menarini and Sanofi Aventis as a drug specialist. Adjunct lecturer in the three-year degree course in Biomedical Laboratory Techniques in the Physical, Chemical and Computer Sciences for the Chemistry Laboratory module MED/46 for the University of Sassari Collaborator of the international cooperation project managed by the University of Sassari and AISPO entitled "Improving the quality of nursing curriculum and clinical practice in Iraqi Kurdistan" (O.I. 239 Co.Pr.2.1.b), with the following roles Conducting assessment with the College of Health Science (University of Duhok) on the Laboratory Technician course, to identify needs and priorities.
Conducting site visits to assess the needs and priorities of the Laboratory Technician course.
Development of an operational proposal to support the Laboratory Technician course.
Assessment of technical equipment needed for the Laboratory

11:00 AM Workshop

M.D. and board-certified in Neurology, Annibale A Puca started as a post-doc at TIGEM, Italy, in 1995 with Prof Brunella Franco. In 1998 he became a postdoc at Harvard Medical School in Prof Louis Kunkel lab. In 2001, in Cambridge, USA, he scientifically directed and co-founded Centagenetix Inc., an early stage start-up. In 2006 he started a group at MultiMedica where he focused its efforts on the discovery of genetic risk factors for exceptional longevity. Actually, he coordinates a group of scientists at the University of Salerno and at MultiMedica. At the academic level, Annibale A Puca became Instructor in Pediatrics at Harvard Medical School in 2001, in 2011 Associate Professor and in 2020 Full Professor in Clinical Pathology at the Department of Medicine of the University of Salerno (now full Professor in Medical genetics). Prof Puca has a strong track record of publications about the genetic component of exceptional longevity and about the therapeutic use of a longevity associated variant (LAV) of BPIFB4.

LAV-BPIFB4, a longevity associated variant 

with potential therapeutic applications

Puca, A. A.1 

1 University of Salerno, Italy

Centenarians of Cilento were analyzed to identify genetic variants able to impact on aging and age-related diseases. The initial Genome Wide Association Study (GWAS) and further replication attempts in independent populations from USA and Germany identified a 4 polymorphisms haplotype homozigous genotype in BPIFB4 enriched in centenarians. Further analysis revealed that the BPIFB4 levels were also elevated in serum of centenarians and that the Longevity Associated Variant-LAV induced BPIFB4 increase in plasma. In vitro and in vivo experiments identified protective effects of LAV-BPIFB4 exposure using gene- and protein-based therapies, pointing to LAV-BPIFB4 as a possible therapeutic tool to prevent and even treat aging and diseases associated with aging. 
11:20 AM Coffee break
12:00 AM Workshop

Francesco Cacciabaudo is Specialist in Food Science, during his formation with the institute of Human Physiology of the University of Palermo, he developed a dietary protocol based on the Ketogenic and Mediterranean diet to be applied on patients suffering from Multiple Sclerosis type RR.
He is lecturer of Human Physiology and Nutrition at the University of Palermo. Since May 2023 he has been attending in the II level master’s degree in Oncological Nutrition at the University of Pavia and he has been collaborating as onco-nutritionist at the Institute of Oncology of University of Palermo.
He is also a PhD in Surgical Biotechnology and Regenerative Medicine in Organ Failure and during his PhD-course he studied the trans-differentiation of the exocrine part of pancreas on pig model to endocrine cells able to produce insulin.
He developed part of his PhD-project, in Germany at the institute of experimental diabetology at the University of Dresden.

Longevity is a complex trait in which genetics, environment, and stochasticity contribute to determine the chance to reach oldness. From many studies gut microbiome has been proposed as a possible determinant of healthy aging. Microbes colonize the neonatal gut immediately following birth. The establishment and interactive development of this early gut microbiota are believed to be driven and modulated by specific compounds present in human milk. Many evidences have linked the breast feeding to certain features of the microbiota, such as maintaining diversity, avoiding aberrant composition and intestinal illnesses in infants or disease states that are manifested at later stages of life, including asthma, inflammatory bowel disease, metabolic disorders and cancer. 
The preservation of host-microbes homeostasis during all life can counteract inflammaging, intestinal permeability, decline in bone and cognitive health. These features are maintained in longevity and extreme longevity associated with the composition of the gut microbiome and its metabolites, primarily through nutrient signaling pathways, immune regulation mechanisms, and epigenetic mechanisms. Thus, aging-related gut dysbiosis may lead to the occurrence or progression of metabolic diseases and cancer. The relationship between cancer and microbes is complex. Although cancer is generally considered to be a disease of host genetics and environmental factors, microorganisms are implicated in ~20% of human malignancies. 
The gut microbiota has a role in detoxification of dietary components, reducing inflammation, and maintaining a balance in host cell growth and proliferation. The ways, in which microbes and the microbiota contribute to carcinogenesis are different such as enhancing or diminishing a host’s risk, fall into three broad categories: altering the balance of host cell proliferation and death, guiding immune system function, influencing metabolism of host produced factors, ingested foodstuffs, and pharmaceuticals. In addition, aging related dietray patterns, can influence gut microbiota health, and dietary interventions can improve intestinal health and immune status, thereby increasing longevity . Furthermore chronic caloric restriction as an healthy life-style may partially extend the lifespan always through its effect on the gut microbiota, increasing beneficial bacteria abundance by decreasing harmful bacteria rather than increasing the diversity of the microbiome.
12:20 AM Workshop

Mattia Emanuela Ligotti is a post-doctoral researcher at University of Palermo, Italy. After graduation in biology, she was a visiting research scientist at the Department of Oncohematology at King's College London, UK, during her PhD, post-Doc at the National Research Council (CNR) in Palermo, Italy, and she is currently a student at the Specialization School in Pathology and Clinical Biochemistry at University of Palermo. Her scientific research is mainly focused in the study of immunosenescence, with special attention on T-cell changes with advancing age in the ultracentenarian, by ex-vivo studies on cell cultures from peripheral blood cells and cytofluorometric analyses. She has co-authored several scientific articles and is part of two ongoing research projects.

Immunonutrition: a way to reach longevity.

Ligotti M.E.1

1Laboratory of Immunopathology and Immunosenescence, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Palermo, Italy.


Individual wellness is closely linked to a functional immune system, able to recognize and eliminate pathogenic microorganisms, infected and cancer cells. However, with advancing age, various age-related functional impairments have been reported in immune response, and they are commonly known as “immunosenescence”.  Among factors contributing towards this phenomenon, nutrition has been shown to play an essential role for both immune cell function and the gut microbiota. Age-related changes in the immune system, their characteristic low-grade inflammation, and gut dysbiosis may relate, at least in part, to age-related changes in nutrition. After all, it is well documented that many older people show changes in the gut microbiota and that nutritional deficiencies or inadequate diet consumption, with no real nutritional value, are closely associated with impaired immune response and loss of the host resistance to infection. For these reasons, the number of studies related to the impact of nutrition on the immune system is continuously increasing. Immunonutrition is an interdisciplinary and emerging field that encompasses aspects related to nutrition, immunity, infection, inflammation and tissue damage. Specific nutritional biocomponents, called immunonutrients, have shown the ability of modulating specific mechanisms involved in several immune and inflammatory pathways. Among the most studied immunonutrients there are a number of macronutrients (omega-3 fatty acids, glutamine, arginine) and micronutrients (vitamins C, D, and E and zinc). It has been widely shown that a proper intake of vitamins and minerals is beneficial for the proper functioning of immune system cells and. This can be achieved with a rich-nutrient well-balanced diet that includes lots of fruits and vegetables. Probiotics and prebiotics also seem to play an important role, acting at the level of the gut microbiota, but there is still no unanimous opinion in the scientific community on their positive effect. However, it should be taken into account that there is not a single parameter to evaluate the cause-effect relationship between nutrition and the immune system and the whole metabolism of the individuals, along with their genetics, their underlying diseases, and even their lifestyles, need to be considered. 
12:40 PM Workshop

I am a PhD student in Biomedicine at the University of Cordoba in the Immunology group at the biomedical research institute IMIBIC where my studies focus on cardiovascular pathologies and the recent SARS-COV-2.

Lifestyle impact in immunosenescence and aortic stenosis

Alvarez-Heredia P.1, Domínguez-del Castillo J.J.1,2, Reina-Alfonso I.1, Gutiérrez-González C.1, Hassouneh F.1, Batista-Duharte A.1, López-Romero R.1,2, Muñoz I.1,2, Solana R. 1, 3 and Pera A.1,3.

1 Maimonides Biomedical Research Institute of Cordoba (IMIBIC) Cordoba, Spain.
2 Cardiovascular Surgery Unit. Reina Sofía university Hospital of Cordoba
3 Department of Cell Biology, Physiology and Immunology, University of Cordoba

Keywords: chronic inflammation, immunosenescence, cardiovascular disease


Cardiovascular disease (CVD) is a global health burden and a leading cause of mortality and morbidity worldwide. Unhealthy habits can lead to dyslipidemia (DLP), high body mass index (BMI), and arterial hypertension (AH). These are known associated factors due to their contribution to the development and progression of CVD. Furthermore, this lifestyle contributes to chronic low-grade inflammation, oxidative stress, and metabolic abnormalities, all of which can ultimately accelerate the immunosenescence process. Immunosenescence is a contributor to the development of atherosclerosis, a chronic inflammatory process characterized by the accumulation of lipids, pro-inflammatory CD28null T cells, immune cells, and fibrous tissue in arterial walls. Inflammation caused by immunosenescence promotes the formation of atherosclerotic plaques, which can lead to the narrowing and blockage of blood vessels. In this context, recent studies suggest that aortic stenosis (AS) is an active inflammatory atherosclerotic-like process. Our group has focused its efforts on characterizing these patients and cross-correlating immunological populations with clinical variables and the progression of AS. We developed a novel cytometry-based protocol for the study of AS that has allowed us to perform, for the first time, an in-depth characterization of the inflammatory infiltrating cell subsets present in the degenerated (calcified) aortic valve. Our findings confirm that AS patients exhibit a higher prevalence of AH, DLP, and elevated BMI compared to healthy donors (HD). Furthermore, our ROC curve analysis demonstrates the impact of the immunosenescence process on the development of aortic stenosis, particularly the decrease in CD28+ T cells which is directly related to immunosenescence. Additionally, Pearson’s correlation analysis reveals the relation between the decrease in CD28+ T cells with higher BMI values. In conclusion, the interplay between DLP, BMI, and AH, as indicators of healthy lifestyle, and immunosenescence, and AS highlights the importance of a comprehensive approach to cardiovascular health. Lifestyle modifications targeting blood pressure control, weight management, healthy eating habits, and regular exercise can help mitigate these risk factors. Furthermore, interventions to modulate immunosenescence and to reduce chronic inflammation may hold promise in preventing and managing not only AS but also other CVDs. Further research is needed to unravel the intricate mechanisms underlying these relationships and to develop effective preventive and therapeutic strategies for CVD.

Figures and Tables

Figure 1. (A) Arterial Hypertension (AH) ratio, Dyslipidemia (DLP) ratio, and Body Mass Index (BMI) in healthy donors (HD) and aortic stenosis (AS) patients. (B) Boxplots of CD4+CD28+CD57neg and CD8+CD28+CD57neg T cells in HD and AS patients (****p-value<0,0001). (C) Receiver operating characteristic curve (ROC) for prediction of aortic stenosis based on the absolute numbers of CD4+CD28+ and CD8+CD28+ T cells. (D) Mann-Whitney U Test table comparing BMI, AH, DLP, CD4+CD28+CD57neg T cells, and CD8+CD28+CD57neg T cells between HD and AS patients. (E) Pearson’s correlation analysis between IMC, CD4+CD28+CD57neg T cells, and CD8+CD28+CD57neg T cells.

Funding: This research was funded by the Spanish Instituto de Salud Carlos III Ministry of Health and co-funded by the European Union, grants PI19/00075 (to Pera A.) and FI20/00194 (to Alvarez-Heredia P.).

1:00 PM Workshop
1:30 PM Lunch
2:30 PM Workshop
Loreto Maciá Loreto Maciá is a University Professor at the University of Alicante. She is a nurse and PhD in public health. 
She is a specialist in service management and her research lines of research are oriented towards the elderly population, health management, innovation, and chronic patients. From 1998 to 2007, she was director of the University School of Nursing at the University of Alicante and between 2009 and 2013, she coordinated the implementation of Bachelor, Master and Doctorate Nursing studies at the Jaume I University of Castellon (Spain).
She collaborates with international higher education certification agencies and coordinates management research at two Spanish universities.
She is currently responsible for the health laboratory of the UCIE ars Innovatio. 

Macià Soler Loreto1

  1. University of Alicante (Spain)


Health management involves analyzing economic costs and quality of life related to health, in all age groups, but especially in older people. Make improvements through research, is a topic under study, because in the environment of the European Union (EU) we have an increasing older population and an inverted demographic pyramid.

According to recent Eurostat data, half of our older population lives in urban settings; and report being in good or very good health. We highlight the highest percentages in Ireland and Sweden and the lowest correspond to Portugal, Latvia and Lithuania.

Regarding the years of healthy life, the latest data from 2021 indicate an average between 60 and 65 years of healthy life with a life expectancy at birth of 77.2 years for men and 82.8 for women.

To maintain healthy years of life and reduce the impact of diseases that may involve health and/or social needs, the EU member states invest a part of their economic funds, but these investments fail to cover all social needs related to dependency, they cover health needs but they do not reach all social needs, since only neurodegenerative diseases that increase with age require high costs.

As an example, only Alzheimer's disease has direct costs in the world of 60 billion dollars annually and indirect costs of 259 billion dollars, which must be added the costs of intangibles. The European average cost of Alzheimer's disease is estimated at 30,000 euros/year.

The prevention of neurodegenerative diseases is complex due to the etiology of the disease, however, there are other age-related diseases that can be prevented or that, once established, through preventive programs, could maintain a level of autonomy or slow down their severity. These are cardiovascular, respiratory, metabolic and osteoarticular diseases where lifestyles become important and consequently the preventive component could be effective. Lifestyles and dependence to carry out basic or instrumental activities of daily life condition healthy aging and consequently the increase in the mentioned pathologies.

 On the other hand, technological usability is increasing in the older population of the 21st century and it makes sense to prevent problems through enabling technologies with greater accessibility and lower cost. In fact, eHealth is one of the fastest growing sectors of the market and could be used locally, nationally or globally as an ingenious means to promote and strengthen health systems and health information.

For these needs of the older population of the 21st century, an adequate management is through the mixture of knowledge and the support of enabling technologies eHealth.

Within eHealth, it is possible to differentiate.

• Mhealth.

• Telehealth.

• Electronic health records

• Social media

• Big data

• Ambient intelligence

Individual health assessment systems with enabling technologies make it possible to identify in less than 30 minutes the state of dependency of the people evaluated and develop solutions that can, at a given moment, help individually or in groups to overcome the dependency of individuals. for each dimension of frailty in the case of aging.

Health, as a good appreciated by humanity since the beginning of time, today has tools that bring professionals and users closer together at a very low cost. The use of technologies for health is an example of being consistent with the objectives of sustainable development and advancing in this digital age.

2:50 PM Workshop

Graduated in Nursing in 2004 and completed the Official master’s degree in Infectious Diseases and International Health at the Miguel Hernández University (2016). In 2021 I obtain a Doctorate in Health Sciences, with an outstanding grade Cum laude. In addition, highlight specific training in teaching improvement and new technologies. I have also completed the Pedagogical Aptitude Course (CAP) of the UA (2005) and the higher degree in Dietetics and Nutrition (2001).
Work and teaching experience:
From 2004 to 2020 I have worked as a nurse in different Specialized Care services (Emergency Services, Internal Medicine, Operating Room, Pharmacy, Medical Specialties, among others) and Primary Care. As a care nurse I have worked in the Health Departments of Elda and Orihuela in the Province of Alicante. I have held health management positions in the Health Department of Elda and Orihuela in the fields of primary and specialized care. I have collaborated with the continuing education commission of both Health Departments, developing and teaching courses at the Valencian School of Health Studies (EVES). Among the courses, those related to infectious diseases, patient safety and quality of care stand out. In the clinical field, I have been part of the Nursing Procedures Commission, the Infectious Diseases Commission and the UFCASP Commission (Functional Unit for Quality of Care and Patient Safety). I start my teaching career in the Nursing Department of the University of Alicante as an assistant professor in 2020. I have published 20 scientific articles and 10 communications to scientific congresses, 1 book chapter and 3 research stays. I am currently part of the GESE group (Management of Nursing Services) of the University of Alicante. My lines of work and research are patient safety, quality of care and technological and educational innovation through the use of electronic tools (e-health) for the development of skills in the field of management and administration of nursing services.

Enabling technologies to improve nutrition in the elderly.

Escandell Rico, F. M.1 

1 University of Alicante, Spain

There is an increase in the global aging of the population that leads to problems of malnutrition, which forces us to cover food needs with preventive actions. Basically, everything revolves around three concepts:

1.-The aging of the population and with it the increase in life expectancy.

2.-The problem of malnutrition, we eat, but we do not eat well.

3.-The Mediterranean diet and technological qualification.

The growing aging of the population is one of the most significant changes that has occurred in developed societies during the second half of the 20th century. Spain's population pyramid continues its regressive evolution, with an increase in the average age and an increase in the proportion of older people. According to the statistical data of the Continuous Register (INE) as of January 1, 2023, there are 9,310,828 million older people, 19.65% of the total population. The growing longevity of the elderly results from a progressive attenuation of the specific mortality rates of this group thanks to the protection of their health. However, social and health care faces new health challenges for the elderly, since they face challenges to improve their quality of life at older ages and the prevalence of other diseases and health risks.

Older people are at risk of compromising nutritional status due to the physical changes associated with aging, as well as cognitive, psychological, and social factors. Loneliness and malnutrition negatively affect quality of life, increase health care costs, and increase the risk of short-term mortality.

Regarding nutrition, the Mediterranean Diet (DM) model, as a quality diet, is associated with a decrease in cardiovascular risk and with the prevention of chronic diseases and some types of cancer. DM is characterized by a high consumption of vegetables, legumes, whole grain cereals, fruits, nuts and a high intake of olive oil (as the main source of fat in the diet). It is also characterized by a moderate consumption of fish, dairy products (with a predominance of yoghurts and cheeses), a low consumption of meat and meat products, and a regular but moderate consumption of wine during meals. There are numerous epidemiological studies that analyze the relationship between diet quality, adherence to the Mediterranean diet, and health in older people. These studies show a decrease in body weight, blood pressure, mortality and an improvement in health-related quality of life.

And finally, when we talk about enabling technologies and their usability to improve nutrition in the elderly, we refer to the implementation of tools that assist and evaluate the nutritional status of the population aged 65+, taking into account adherence to DM and facilitating daily and personalized monitoring of nutritional status.
3:10 PM Workshop

Manuel Platero Horcajadas is Associate Professor at the University of Alicante for the Department of Information Technology and Communication.

He has worked for 4 years in different health innovation projects at the UCIE Arsinnovatio health innovation laboratory. During these 4 years she has investigated the use of digital assistants, how to prepare personalised solutions and how to use them with elderly people.

Digital assistants to combat loneliness and promote a personalised Mediterranean diet in the elderly.

Manuel Platero Horcajadas1
1Dept Tecnología Informática y Computación. Universidad de Alicante, Spain

This project proposes the use of digital assistants and chatbots to help older people follow a Mediterranean diet, which has health benefits and prevents chronic diseases. Digital assistants and chatbots can provide personalized advice, nutritional information, adapted recipes and daily reminders, as well as combat loneliness and promote an active lifestyle. These technologies can improve the health and well-being of older people, facilitating adherence to a balanced diet and providing constant support. 

Sustainable development goals and targets

This congress is aligned with the following SDGs


We would like to thank Antonella Aiello for the creation of the congress logo.


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  • Sala delle Capriate, Palermo